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BREAKTHROUGHS

HAVE YOU HAD YOUR PNEUMOCOCCAL VACCINE?

If you have coeliac disease, you might be at risk of reduced spleen function and serious infection. Research now points to the vaccine that will help.

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Researchers believe pneumococcal vaccination is important for everybody with coeliac disease to reduce the risk of serious infection.
Research has found that people with coeliac disease will benefit from pneumococcal vaccination.

The team at WEHI – Walter and Eliza Hall Institute of Medical Research have recently published the results of a study seeking to understand hyposplenism in coeliac disease. The study, led by Associate Professor Jason Tye-Din, was supported by Coeliac Australia’s research funding program and was the first to systematically study spleen function in Australians with coeliac disease.

Importantly, the study found that individuals with coeliac disease will be better protected against serious infection if vaccinated against pneumococcus.

While the study found that hyposplenism is relatively uncommon in those with coeliac disease, it did discover that the function of IgM Memory B Cells (our first line defense against infection) is more likely to be impaired.

“We showed more than a third of adults, despite having well-treated coeliac disease, had evidence of suboptimal B cell function meaning their capacity to make antibodies to the pneumococcus bacteria was reduced,” says Dr Tye-Din.

This highlights the importance of pneumococcal vaccination to protect against serious infection. While included as part of the routine vaccination schedule for children, adult vaccination is now also recommended. The next step is to incorporate these recommendations into clinical practice guidelines to help reduce complications from coeliac disease.

Read the article below for more information https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10891918/

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1 Comment

  1. Olivia Curtain
    Olivia Curtain on November 29, 2023 at 12:45 pm

    How do I get the vaccination?

    Reply

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